新学術領域研究(研究領域提案型) 脳タンパク質老化と認知症制御

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国際学会

⬛︎2016

  1. Takashima A.:Mechanism of Neurodegeneration through Tau and Therapy for AD.(Keynote speaker)The 7th International High Level Forum on Exercise and Health – International Conference of Exercise Intervention on Alzheimer’s disease (ICEIAD),2016,5.7-8 , Shanghai, China
  2. 18. Hideyuki Okano : Challenge toward Spinal Cord Injury using iPS cell Technologies.: CiRA/ISSCR 2016 International Symposia,(Kyoto University Clock Tower Centennial Hall) 2016.3.24 Kyoto, Japan
  3. Matsumoto, G. Nukina, N. Mori, N.: p62-mediated selective autophagy in aged neurons, The 6th Busan-Nagasaki Joint Seminar on Aging Research, Seacloud Hotel in Busan,2016,3.11 South Korea 
  4. Furukawa Y:Protein conformational disorder leading to neurodegenerative diseases. The 3rd Mini-Symposium on Cutting-Edge Chemistry,2016,3.11 Hsinchu, Taiwan
  5. Takashima A.:Mechanism of Neurodegeneration through Tau and Therapy for AD.(symposium) The 1st International Gachon Neuroscience Symposium,2016,2. 24.Incheon, Korea.
  6. Okano H : Challenge toward Spinal Cord Injury and using iPS cell Technologies UK-JAPAN Life Innovation Symposium. : UK-JAPAN Life Innovation Symposium, (Tokyo Branch Kyoto University & LiSE KING SKYFRONT)2016.2.22 Sinagawa & Kawasaki, Japan

⬛︎2015

  1. Okano H : Modeling Human Neurological/Psychiatric Diseases using iPS cells and Transgenic Non-Human Primates. : Regenerative Medicine Seminar Series@Stanford,(Stanford University, Stanford) 2015.12.10 CA, USA
  2. Fukata M : Postsynaptic nanodomain regulated by PSD-95 palmitoylation machinery. Pacifichem 2015, 2015.12.15 Honolulu, HI, USA
  3. Okamura N:Busan Paik Hospital Neurodegenerative Disease Symposium, 2015, 11. 27, Busan
  4. Okano H : Modeling Psychiatric/Neurological disorders using iPS cell technologies and transgenic non-human primates. : THE 12TH NIKKO INTERNATIONAL SYMPOSIUM 2015 FRONTIERS IN TRANSLATIONAL NEUROSCIENCE,(JMU Education & Research Center) 2015.11.20 Shimotsuke, Japan
  5. Okano H : Transgenic and Genome Editing Technologies in Non-Human Primates. : TGE2015 Conference on Transposition and Genome Engineering 2015, Invited Lecture,(Nara Kasugano International Forum IRAKA)2015.11.19 Nara, Japan
  6. Mochizuki H :Parkinson’s disease and α-synuclein. Australian National University (ANU) & IPR Joint Symposium 2015 “PROTEIN STRUCTURE AND FUNCTION”.2015,11.16. Australia.
  7. Okano H : Preemptive Approaches for Neurodegenerative Disease and Dementia : 2015 WAFSF “Regenerative Medicine: Let’s Talk Business!”(Golden Gate Club)2015.11.12 San Francisco, USA
  8. Okano H : Modeling Psychiatric/Neurological disorders using iPS cell technologies and transgenic non-human primates.: 29th Annual Conference of he International Mammalian Genome Society, Keynote Lecture, (Yokohama Port Opening Memorial Hall) 2015.11.11. Yokohama, Japan
  9. Okano H : Modeling psychiatric/neurological disorders using ips cell technologies and transgenic non-human primates. : Cell Symposia:Human Genomics, (the Matrix building, 30 Biopolis Street)2015.11.9.Singapore
  10. Shimizu S “Biological Roles of Autophagic Cell Death”Japan Australia Meeting on Cell Death.2015,10.21-23 Melbourne
  11. Okamura N:2015 IPA 17th International Congress , 2015,10. 15, Berlin
  12. Yamaguchi Y: RIKEN-ACADEMIA Sinica Joint Conference on Chemical Biology, Taipei,2015,10.14-17 Taiwan
  13. Okano H : Modeling Neurological Diseases using iPS cells and Transgenic Non-human Primates. : The first International Symposium of Brain Protein Aging and Dementia Control, (Noyori Conference Hall),2015.10.10.Nagoya, Japan
  14. Hasegawa M: Molecular analyses of pathological tau in tauopathy brains. Brain Protein Aging and Dementia Control. 1st International Symposium. Molecular bases of brain protein aging. 2015. 10.9, Nagoya
  15. Onodera O:How does the cerebral small vessel system contribute the brain function in aging?–Lesson from the hereditary small vessel disease–Brain Protein Aging and Dementia Control 1st International Symposium 2015.10.9 Nagoya
  16. Okano H, Matsuo H, Nishimura Y, Hozumi K,Yoshioka S,Tonoki A, Itoh M, Ubiquitination of Dynamin 2 and Snx18 by Mib1 promotes Dll1 endocytosis and Notch signaling.
    Notch meeting, 2015,10.7 Athens,Greece
  17. Okano H : Preemptive Medicine for Dementia: Solutions for a ‘super-aging’ society. : International Conference on Cognitive Decline and Its Economic Consequences 国際会議「認知症社会における経済的挑戦と機会」, (North uilding Hall on Mita Campus, Keio University)
    2015.10.5 Tokyo, Japan
  18. Okano H : Regenerative Medicine and Disease Modeling with iPS cells technologies. :1th Annual Meeting of Korean Society for Stem Cell Research”Presidential Session -Today’s Stem Cell Research in Asia,(Grand Hilton Seoul Hotel) 2015.8.28,Seoul, Korea
  19. Okano H : Modeling Human Neurological Diseases using iPS cells and Transgenic Non-Human Primates : CHA Bio Complex Seminar, (CHA Bio Complex)2015.8.27 Seoul, Korea
  20. Hisanaga S, Kimura T: Reevaluation of physiological and pathological phosphorylation of tau in vitro to human brains 25th International Society for Neurochemistry,2015.8.23-25. Cairns, Australia,
  21. Okano H : Modeling Human Neurological/Psychiatric Disorders using iPS cells and Transgenic Non-Human Primates. : Breakthroughs in Molecular Genetics in Model Organisms Symposium,(UC Santa Barbara)2015.8.22 Santa Barbara, CA, USA
  22. Fukata M:Regulatory mechanism for local palmitoylation cycles on PSD-95. FASEB Science Research Conference “Protein Lipidation, Signaling, and Membrane Domains 2015.7.22 Saxtons River, VT, USA)
  23. Okano H: Neuronal damage and regenerative medicine. : Center for Animal Disease Model International Symposium (CADMIS) 2015—Frontiers of Immunology and Neurobiology—(東京理科大学ヒト疾患モデル研究センター国際シンポジウム), 2015.7.21 Tokyo
  24. Furukawa Y:Lights and shadows of Cu,Zn-superoxide dismutase. The 17th International Conference on Biological Inorganic Chemistry,2015,7.20-24 Beijing, China
  25. Sobue G:Novel Imaging biomarker for early detection AD.International Symposium on Alzheimer’s Disease Prevention Strategy in Search of the Road to New Hrizon.
    2015.6.27 Tokyo
  26. Okano H : Modeling neurological and psychiatric disorders using iPSCs technologies and transgenic non-human primates. : The ISSCR Annual Meeting,(Stockholmsmassan Exhibition and Convention Center)2015.6.25 Stockholm, Sweden
  27. Okano H : Brain Mapping Project in Japan:Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/ MINDS). : Cold Spring Harbor Asia (CSHA) Conference on International Brain Project,(Suzhou Industrial Park Conference Center, Suzhou, People’s Republic of China, PRC)2015.6.19 Suzhou、China
  28. Okano H : Disease Modeling and Brain Mapping using transgenic marmosets. : Janelia Marmoset Workshop ”The common marmoset as a transgenic model of the human brain in health and disease”,(Janelia Research Campus, Howard Hughes Medical Institute)2015.6.16 Virginia, USA
  29. Murakami T: Alteration of corticobulbar excitability during speech perception. International TMS Symposium 2015.6.7, Fukushima
  30. Okamura N: SNMMI 2015 Annual Meeting, 2015,6.6,Baltimore
  31. 4. Hideyuki Okano : Using Genetics to Deconstruct Neural Circuits session Alpbach Congress Centrum in Alpbach(2016 Keystone Symposia on The Brain, Austria)2015.05.23-27 Alpbach,Austria
  32. Yamaguchi Y :RIKEN-Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium,2014,5.21-24 Kreuth, Germany
  33. Okano H : Brain Mapping and Modeling Human Psychiatric/Neurological Disorders using Transgenic technologies and Genome-Editing in Non-human Primates.(Scientific meeting on animal models of neurodegenerative Disorders) 2015.05.02.Paris, France)
  34. Okano H : Brain Science and Modeling Neurological Diseases using Transgenic and Genome Editing Technologies. : Dr. Austin Smith Lab Seminar,(Stem Cell Institute, University of Cambridge),2015.4.22 Cambridge, UK
  35. Okano H : Modeling Human Psychiatric/Neurological Disorders using Transgenic technologies and Genome-Editing in Non-human Primates. (24 th annual Colloque Médecine et Recherche in the Neurosciences series,FranceGenome Editingin Neurosciences) #Cloud ,2015.04.21.Paris
  36. Okano H : Modeling Psychiatric/Neurological disorders using iPS cell technologies and transgenic non-human primates.International Symposium on Cell Physiology and Aging Research  Kaohsiung Medical University (KMU),2015,4.12 Kaohsiung, Taiwan
  37. Hisanaga, S:Neuronal protein kinase LMTK1 regulates neurite outgrowth through Rab11-dependent endosomal trafficking in a Cdk5-dependent manner EMBO Workshop,
    2015.3.23-26,PUERTO MONTT, Chile,
  38. Okamura N: ADPD Imaging Symposium 2015, 2015,3. 17, Nice
  39. Takashima A: Aging and Tau (symposium)Asian Aging Core for Longevity (AACL) 10 years and Beyond Japan-Korea Joint Seminars, Osaka, Japan. 2015,3.12, 2015
  40. Okano H:Brain Science using Transgenic non-Human Primates:第5回新潟大学脳研究所共同研究拠点国際シンポジウム BRI International Symposium 2015 Genome Editing Technology; its Current State-of-Art and Application to Brain Research, Keynote lecture, (Center for Integrated Human Brain Science (6F), Niigata University)2015.3.6 Niigata
  41. Okano H : Cell transplantation therapies for spinal cord injury focusing on human iPS cells.The 18th Takeda Science Foundation Symposium on Bioscience”iPS Cells for Regenerative Medicine”, (Center for Learning and Innovation (CLI), Takeda Pharmaceutical Company, Ltd.) 2015.1.15 Suita

⬛︎2014

  1. Suhara T, Nagai Y, Yukiko H, Ji B, Higuchi M, Minamimoto T: In vivo imaging of designer receptor that enables to modify cell function and reward-related behavior in monkeys, NSFC-CAS-JSPS International Workshop on Frontier of Science and Technology 2014, 2014.12.06, China
  2. Okano H: Modeling psychiatric/neurological disorders using iPS cell technologies and transgenic non-human primates. : BROAD Institute Seminar, Auditorium, BROAD Institute,2014.12.4 MA, USA
  3. Sahara N,Ono M, Koga S, Maeda J,Matsumoto I, Dennis W. Dickson, Zbigniew K. Wszolek, Ming-Rong Zhang, Suhara T, Higuchi M:Visualization of tau lesions in brains of tauopathy patients and model mice using tau ligand PBB3 2014北米神経科学学会, 北米神経科学会, 2014-11-17(本発表はSFN2014, Hot Topicsに選出) Washington, DC,USA
  4. Fujioka Y,Ishigaki S,Shiromizu T, Udagawa T, Yokoi S, Honda D, Ikenaka K,Katsuno M,Tomonaga T and Sobue G: The involvement of glial cells in FUS-related ALS/FTLD pathophysiology –FUS knock-down glial cells have a neuro-protective effect.The 43rd Society for Neuroscience annual meeting,2014.11.15-19 Washington DC,
  5. Okano H : Transgenic marmosets for modeling human nuerological and psychiatric disorders: Minisymposium 668 “Transgenic Primate Models of Human Brain” at Neuroscience 2014,(the Walter E. Washington Convention Center)2014.11.19 Washington DC, USA
  6. Okano H : Transgenic marmosets for modeling human nuerological and psychiatric disorders: Minisymposium 668 “Transgenic Primate Models of Human Brain” at Neuroscience 2014(the Walter E. Washington Convention Center)2014.11.19 Washington DC, USA
  7. Okano H : Brain Mapping Project in Japan:Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/ MINDS). : the Public Advocacy Forum at Neuroscience 2014,(the Walter E. Washington Convention Center)2014.11.18 Washington DC, USA
  8. Okano H : Brain Mapping by Integrated Neurotechnologies for disease Studies. : Marmoset Social,(Renaissance Washington, DC Downtown Hotel) 2014.11.17 Washington DC, USA
  9. Hideyuki Okano : iPS Cell Technologies:Significance and Applications to CNS Regeneration and Disease Research. :2014 WASF on Stem Cell Research and Regenerative Medicine “The Impact of Regenerative Medicine 2014”,Mission Bay Converence Center at UCSF,2014.11.6 San Francisco, USA
  10. Hasegawa M: Prion-like properties of pathological proteins from diseased brains. Brain Conference 2014, Symposium 4「Pathological propagation in neurodegenerative diseases」2014.11.6 Seoul, Korea
  11. Okano H: iPS Cell Technologies:Significance and Applications to CNS Regeneration and Disease Research. :2014 WASF on Stem Cell Research and Regenerative Medicine “The Impact of Regenerative Medicine 2014”(Mission Bay Converence Center at UCSF) 2014.11.6 San Francisco, USA
  12. Okano H : Application of human iPS cells for inner ear biology and human disease modelin. :Inner Ear Biology Workshop 2014 in Kyoto, Lecture, (Kyoto International Conference Center)2014.11.3 Kyoto, Japan
  13. Okamura N:Tau and Amyloid Imaging. Outlook for the Future. EANM 2014,2014.10.21,  Gothenburg, Sweden
  14. Okamura N, Furumoto S, Harada R, Tago T, Iwata R, Tashiro M, Furukawa K, Arai H, Yanai K, Kudo Y:Characterization of [18F]THK-5351, a novel PET tracer for imaging tau pathology in Alzheimer’s disease. EANM 2014, 2014.10.21 Gothenburg, Sweden
  15. Okamura N:Tau-Imaging. Results of First-in Human Studies. EANM 2014 Pre-Congress Symposium 6: TAU and Amyloid: From Neuropathology to Neuroimaging,2014.10.18 Gothenburg, Sweden
  16. Okano H: Modeling neurological and psychiatric disorders using iPSC technologies and transgenic non-human primates. : BRIDGING BIOMEDICAL WORLDS (BBW 2014) – Turning obstacles into opportunities for stem cell therapy, (China National Convention Center),
    2014.10.14 Beijing, PR China
  17. Sugai A,Kato T, Koyama A, Nishizawa M, Onodera O: Endogenous TDP-43 over-expression model with disrupted auto-regulation : 10th Annual Meeting of the Oligonucleotide Therapeutics Society.Hilton San Diego Resort & Spa,2014,10.12-15 San Diego, California
  18. Okamura N:Imaging neurofibrillary pathology in Alzheimer’s disease using novel tau PET tracer. 14th ICGP & 19th JSNP Joint Congress, 2014.10.3 Tsukuba, Japan
  19. Okano H : The Brain Mapping Project in Japan: Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/ MINDS). : Human Brain Project (HBP) Summit 2014, Kirchhoff Institute for Physics(KIP),2014.9.29 Heidelberg, Germany
  20. Sahara N : Tau PET imaging: New insight into early diagnosis of tauopathy 2nd International Conference on Alzheimer”s Disease & Dementian,
    OMICS Publishing Group, 2014-09-23
  21. Takashima A: Tau /tau interaction through Cys residue form a toxic tau aggregate.(symposium)7th Asian Aging Core for Longevity (AACL) conference in Jeju,2014,9.22 Jeju, Korea.
  22. Hasegawa M: Prion-like features in alpha-synucleinopathies. XVIIIth International Congress of Neuropathology 2014. W3: Prion-like mechanisms in neurodegenerative disorders.2014.9.15 Rio de Janeiro, Brazil
  23. Osamu O, Masatoyo N, Hitoshi T: Update in amyotrophic lateral sclerosis: he XVIII International Congress of Neuropathology. ICN 2014, Rio de Janeiro, Brazil, 2014.9.14-18
  24. Hasegawa M: Pathological alpha-synuclein spreading explains the disease progression. Neuroscience 2014. Joint Symposium of the Japan Neuroscience Society and the Korean Society of Brain and Neuroscience: Molecular Mechanisms underlying Parkinson Disease.2014,9.12 Yokohama,Japan
  25. Okano D : Modeling neurological and psychiatric disorders using iPSC technologies and transgenic non-human primates. BRIDGING BIOMEDICAL WORLDS (BBW 2014) – Turning obstacles into opportunities for stem cell therapy,China National Convention Center (CNCC),2014.10.14 Beijing, PR China
  26. Sahara N:Tau imaging.the frontier of neuroimaging in neurodegenerative disease
    Autonomous University of Madrid セミナー, 2014-09-26 Madrid,Spain
  27. 2. Suhara T:In vivo Tau PET Imaging Using[11C]PBB3 in Alzheimer’s Disease and Non-Alzheimer’s Disease Tauopathies, 2014 Taiwan International Symposium of Molecular Imaging and 2014 Annual Meeting of Taiwanese Society for Molecular Imaging, 2014.09.12, Taipei
  28. Ishigaki S, Fujioka Y, Udagawa T, Honda D, Yokoi S, Katsuno M, Okado H, and Sobue G:Quality loss of FUS and SFPQ in the nucleus causes FTLD-like behavioral abnormalities by modulating Tau isoforms. The 37th annual Meeting of the Japan Neuroscience Society 2014.9.11-13 Yokohama, Japan
  29. Fujioka Y,Ishigaki S,Shiromizu T, Udagawa T, Yokoi S, Honda D, Ikenaka K, Katsuno M, Tomonaga T, and Sobue G:The involvement of glial cells in FUS-related ALS/FTLD pathology-FUS knock-down glial cells have a neurotrophic effect.The 37th annual Meeting of the Japan Neuroscience Society 2014.9.11-13 Yokohama, Japan
  30. Koyama A, Sugai A, Kato T, Konno T,Ishihara T, Nishizawa M, Onodera O: TDP-43 is autoregulated by multiple excisions of introns in exon6 and reservation of mRNA in nucleus by TDP-43. The 37th Annual Meeting of the Japan Neuroscience Society. 2014,9.11-13 Yokohama
  31. Shiga A, Kondo C, Hirokawa S, Tsukie T, Miyashita A, Nishizawa M, Onodera O: Alternation of miRNA expression in TDP-43 depleted spinal motor neuron. The 37th Annual Meeting of the Japan Neuroscience Society. 2014,9.11-13 Yokohama
  32. Kato T,Koyama A, Sugai A, Toyoshima Y, Takahashi H, Nishizawa M, Onodera O: Analysis of intracellular distribution of TDP-43 mRNA in affected spinal motor neuron with ALS. The 37th Annual Meeting of the Japan Neuroscience Society.2014,9.11-13 Yokohama
  33. Onodera O: RNA metabolism and ALS. The 37th Annual Meeting of the Japan Neuroscience Society.2014,9.11-13 Yokohama
  34. Hisanaga, S., Kimura, T:Reevaluation of physiological and pathological phosphorylation of tau in vitro to human brains 25th ISN meeting,2015,8. 23-25 Cairns, Australia,
  35. Takahashi M, Nonaka T, Kametani F, Hisanaga S, Hasegawa M:Treatment of cells expressing APP with tau fibrils induces intracellular aggregate formation of tau. Alzheimer’s Association International Conference (AAIC2014); 2014. 7. 16. Copenhagen, Denmark
  36. Nonaka T, Masai H, Hasegawa M:Phosphorylation of TDP-43 by casein kinase 1 delta facilitates mislocalization and intracellular aggregate formation of TDP-43. Alzheimer’s Association International Conference (AAIC2014); 2014. 7. 15. Copenhagen, Denmark
  37. Ono M, 季 斌, Sahara N, Tokunaga M, Komatsu M,Tanaka K,Ichikawa M,Warabi E, Suhara T, Higuchi H:Pivotal roles of p62 and selective autophagy in neurodegeneration revealed with tauopathy mouse models Alzheimer’s Association International Conference, 2014 Alzheimer’s Association, 2014-07-15 Toronto, Canada
  38. Sahara N,Wen-Lang Lin, Perez Pablo,Higuchi H,Suhara T, Marcelo Febo :Age-related white matter pathogenesis in a mouse model of Tauopathy Alzheimer’s Association International Conference 2014, Alzheimer’s Association,2014,7.15 Toronto, Canada
  39. Takashima A: Granular tau oligomer as toxic tau aggregation form in AD.
    Alzheimer’s Association International Conference 2014, Copenhagen, Denmark. 2014,7.14,
  40. Sahara N, Wen-Lang Lin, Perez Pablo, Higuchi M, Suhara T, Marcelo Febo:Age-related white matter pathogenesis in a mouse model of Tauopathy Alzheimer’s Association International Conference 2014, Alzheimer’s Association,2014-07-13 Toronto, Canada
  41. Okamura N, Harada R, Furumoto S, Furukawa K, Ishiki A,Tomita N, Tashiro M, Iwata R, Yanai K, Arai H, Kudo Y:Comparison of 18F-THK5117 and 11C-PiB PET images in the patients with Alzheimer’s disease. AAIC 2014, 2014.7.12-17,Copenhagen
  42. Harada R, Okamura N, Furumoto S, Tago T, Yoshikawa T,Akatsu H, Arai H, Iwata R, Yanai K, Kudo Y:Binding characterization of tau PET tracer 18F-THK5117 in non-Alzheimer’s neurodegenerative diseases. AAIC 2014,2014.7.12-17, Copenhagen
  43. Okano H : Brain science using iPS Cell technology and transgenic non-human primates. 29th CINP World Congress of Neuropsychopharmacology (CINP-The International College of Neuropsychopharmacology), Plenary Lecture, Vancouver Centre,2014.6.24 Vancouver, Canada
  44. Hasegawa M: Prion-like propagation of pathological proteins in neurodegenerative diseases. 2014 Yonsei BK21 PLUS – Igakuken Joint Symposium,2014, 6. 19.Seoul, Korea
  45. Okamura N, Furumoto S, Harada R, Furukawa K, Ishiki A, Iwata R, Tashiro M, Yanai K, Arai H, Kudo Y: In vivo selective imaging of tau pathology in Alzheimer’s disease with 18F-THK5117. SNMMI 2014 Annual Meeting, 2014.6. 9, St. Louis
  46. Okamura N: Advances in Tau PET. SNMMI 2014 Annual Meeting, 2014.6. 8, St. Louis